Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis

Post-translational histone modifications modulate chromatin activity to affect gene expression. How chromatin states underlie lineage choice in single cells is relatively unexplored. We develop sort-assisted single-cell chromatin immunocleavage (sortChIC) and map active (H3K4me1 and H3K4me3) and rep...

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Detalles Bibliográficos
Autores principales: Zeller, Peter, Yeung, Jake, Viñas Gaza, Helena, de Barbanson, Buys Anton, Bhardwaj, Vivek, Florescu, Maria, van der Linden, Reinier, van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925381/
https://www.ncbi.nlm.nih.gov/pubmed/36539617
http://dx.doi.org/10.1038/s41588-022-01260-3

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