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Durvalumab with or without tremelimumab in patients with persistent or recurrent endometrial cancer or endometrial carcinosarcoma: A randomized open-label phase 2 study
INTRODUCTION. Our understanding of the biologic heterogeneity of endometrial cancer has improved, but which patients benefit from single-agent versus combination immune checkpoint blockade remains unclear. METHODS. We conducted a single-center, randomized, open-label, phase 2 study of durvalumab 150...
Autores principales: | Rubinstein, Maria M., Doria, Eric Rios, Konner, Jason, Lichtman, Stuart, Zhou, Qin, Iasonos, Alexia, Sarasohn, Debra, Troso-Sandoval, Tiffany, Friedman, Claire, O'Cearbhaill, Roisin, Cadoo, Karen, Kyi, Chrisann, Cohen, Seth, Soldan, Krysten, Billinson, Eric, Caird, Imogen, Jang, Dasom, Eid, Khalil, Shah, Pooja, Guillen, Joyce, Aghajanian, Carol, Zamarin, Dmitriy, Makker, Vicky |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925401/ https://www.ncbi.nlm.nih.gov/pubmed/36512912 http://dx.doi.org/10.1016/j.ygyno.2022.11.028 |
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