Tanshinone IIA-loaded nanoparticles and neural stem cell combination therapy improves gut homeostasis and recovery in a pig ischemic stroke model

Impaired gut homeostasis is associated with stroke often presenting with leaky gut syndrome and increased gut, brain, and systemic inflammation that further exacerbates brain damage. We previously reported that intracisternal administration of Tanshinone IIA-loaded nanoparticles (Tan IIA-NPs) and tr...

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Detalles Bibliográficos
Autores principales: Jeon, Julie H., Kaiser, Erin E., Waters, Elizabeth S., Yang, Xueyuan, Lourenco, Jeferson M., Fagan, Madison M., Scheulin, Kelly M., Sneed, Sydney E., Shin, Soo K., Kinder, Holly A., Kumar, Anil, Platt, Simon R., Ahn, Jeongyoun, Duberstein, Kylee J., Rothrock, Michael J., Callaway, Todd R., Xie, Jin, West, Franklin D., Park, Hea Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925438/
https://www.ncbi.nlm.nih.gov/pubmed/36781906
http://dx.doi.org/10.1038/s41598-023-29282-9

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