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Annexin A1 (Ac2-26)-dependent Fpr2 receptor alleviates sepsis-induced acute kidney injury by inhibiting inflammation and apoptosis in vivo and in vitro

OBJECTIVES: Excessive inflammatory responses and apoptosis are critical pathologies that contribute to sepsis-induced acute kidney injury (SI-AKI). Annexin A1 (ANXA1), a member of the calcium-dependent phospholipid-binding protein family, protects against SI-AKI through its anti-inflammatory and ant...

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Detalles Bibliográficos
Autores principales: Zheng, Yanlei, Li, Yan, Li, Shi, Hu, Ronghua, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925514/
https://www.ncbi.nlm.nih.gov/pubmed/36544058
http://dx.doi.org/10.1007/s00011-022-01640-9