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Enzyme-like polyene cyclizations catalyzed by dynamic, self-assembled, supramolecular fluoro alcohol-amine clusters

Terpene cyclases catalyze one of the most powerful transformations with respect to efficiency and selectivity in natural product (bio)synthesis. In such polyene cyclizations, structurally highly complex carbon scaffolds are built by the controlled ring closure of linear polyenes. Thereby, multiple C...

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Detalles Bibliográficos
Autores principales: Arnold, Andreas M., Dullinger, Philipp, Biswas, Aniruddha, Jandl, Christian, Horinek, Dominik, Gulder, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925744/
https://www.ncbi.nlm.nih.gov/pubmed/36781877
http://dx.doi.org/10.1038/s41467-023-36157-0