Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment

The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) is a complex ecosystem that drives tumor progression; however, in-depth single cell characterization of the PDAC TME and its role in response to therapy is lacking. Here, we perform single-cell RNA sequencing on freshly coll...

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Detalles Bibliográficos
Autores principales: Werba, Gregor, Weissinger, Daniel, Kawaler, Emily A., Zhao, Ende, Kalfakakou, Despoina, Dhara, Surajit, Wang, Lidong, Lim, Heather B., Oh, Grace, Jing, Xiaohong, Beri, Nina, Khanna, Lauren, Gonda, Tamas, Oberstein, Paul, Hajdu, Cristina, Loomis, Cynthia, Heguy, Adriana, Sherman, Mara H., Lund, Amanda W., Welling, Theodore H., Dolgalev, Igor, Tsirigos, Aristotelis, Simeone, Diane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925748/
https://www.ncbi.nlm.nih.gov/pubmed/36781852
http://dx.doi.org/10.1038/s41467-023-36296-4

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