Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity

Unlike PIWI-interacting RNA (piRNA) in other species that mostly target transposable elements (TEs), >80% of piRNAs in adult mammalian testes lack obvious targets. However, mammalian piRNA sequences and piRNA-producing loci evolve more rapidly than the rest of the genome for unknown reasons. Here...

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Detalles Bibliográficos
Autores principales: Sun, Yu H., Cui, Hongxiao, Song, Chi, Shen, Jiafei Teng, Zhuo, Xiaoyu, Wang, Ruoqiao Huiyi, Yu, Xiaohui, Ndamba, Rudo, Mu, Qian, Gu, Hanwen, Wang, Duolin, Murthy, Gayathri Guru, Li, Pidong, Liang, Fan, Liu, Lei, Tao, Qing, Wang, Ying, Orlowski, Sara, Xu, Qi, Zhou, Huaijun, Jagne, Jarra, Gokcumen, Omer, Anthony, Nick, Zhao, Xin, Li, Xin Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925758/
https://www.ncbi.nlm.nih.gov/pubmed/36781861
http://dx.doi.org/10.1038/s41467-023-36354-x

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