Cargando…

Identification of a hypoxia-related gene prognostic signature in colorectal cancer based on bulk and single-cell RNA-seq

Colorectal cancer (CRC) is the most common and fatal tumor in the gastrointestinal system. Its incidence and mortality rate have increased in recent years. Hypoxia, a persistent physiological tumor feature, plays a vital role in CRC tumorigenesis, metastasis, and tumor microenvironment (TME). Theref...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiao, Yihuan, Jiang, Xunliang, Li, Yaoting, Wang, Ke, Chen, Rujie, Liu, Jun, Du, Yongtao, Sun, Li, Li, Jipeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925779/ https://www.ncbi.nlm.nih.gov/pubmed/36781976 http://dx.doi.org/10.1038/s41598-023-29718-2

Ejemplares similares

Integrating single-cell RNA-seq and bulk RNA-seq to construct prognostic signatures to explore the role of glutamine metabolism in breast cancer
por: Pei, Shengbin, et al.
Publicado: (2023)

Single‐cell RNA‐seq and bulk RNA‐seq explore the prognostic value of exhausted T cells in hepatocellular carcinoma
por: Tang, Xiaolong, et al.
Publicado: (2023)

EZH2-H3K27me3-mediated silencing of mir-139-5p inhibits cellular senescence in hepatocellular carcinoma by activating TOP2A
por: Wang, Ke, et al.
Publicado: (2023)

Combined bulk RNA-seq and single-cell RNA-seq identifies a necroptosis-related prognostic signature associated with inhibitory immune microenvironment in glioma
por: Wan, Sicheng, et al.
Publicado: (2022)

Development of a Comprehensive Gene Signature Linking Hypoxia, Glycolysis, Lactylation, and Metabolomic Insights in Gastric Cancer through the Integration of Bulk and Single-Cell RNA-Seq Data
por: Zhang, Xiangqian, et al.
Publicado: (2023)

Identification of Five Glycolysis-Related Gene Signature and Risk Score Model for Colorectal Cancer
por: Zhu, Jun, et al.
Publicado: (2021)

Integrating Bulk-seq and Single-cell-seq Reveals Estrogen and MAPK Pathways Associating with Neuroblastoma Outcome
por: Li, Xin, et al.
Publicado: (2023)

Targeting the E3 ligase NEDD4 as a novel therapeutic strategy for IGF1 signal pathway-driven gastric cancer
por: Wang, Ke, et al.
Publicado: (2023)

Unveiling mitophagy-mediated molecular heterogeneity and development of a risk signature model for colorectal cancer by integrated scRNA-seq and bulk RNA-seq analysis
por: Gao, Han, et al.
Publicado: (2023)

Prognostic value of a hypoxia-related microRNA signature in patients with colorectal cancer
por: Yang, Yongmei, et al.
Publicado: (2020)

Identification of Candidate Genes Associated With Hypoxia Tolerance in Trachinotus blochii Using Bulked Segregant Analysis and RNA-Seq
por: Liu, Yifan, et al.
Publicado: (2021)

Integration of single-cell and bulk RNA sequencing to establish a prognostic signature based on tumor-associated macrophages in colorectal cancer
por: Li, Hua, et al.
Publicado: (2023)

Identification and validation of a hypoxia-related prognostic signature in clear cell renal cell carcinoma patients
por: Li, Zhengtian, et al.
Publicado: (2021)

Integrated Analysis of Single-Cell RNA-Seq and Bulk RNA-Seq Combined with Multiple Machine Learning Identified a Novel Immune Signature in Diabetic Nephropathy
por: Peng, Yue-Ling, et al.
Publicado: (2023)

Hypoxia-based classification and prognostic signature for clinical management of hepatocellular carcinoma
por: Li, Ke, et al.
Publicado: (2023)

Integrative Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unveils Novel Prognostic Biomarkers in Multiple Myeloma
por: Zhao, Jing, et al.
Publicado: (2022)

ScRNA-seq and bulk RNA-seq reveal the characteristics of ferroptosis and establish a risk signature in cholangiocarcinoma
por: Yao, Wenchao, et al.
Publicado: (2022)

Integrative Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unveils the Characteristics of the Immune Microenvironment and Prognosis Signature in Prostate Cancer
por: Wang, Ruisong, et al.
Publicado: (2022)

Integrated analysis of single‐cell RNA‐seq dataset and bulk RNA‐seq dataset constructs a prognostic model for predicting survival in human glioblastoma
por: Lai, Wenwen, et al.
Publicado: (2022)

A novel cuproptosis-related prognostic gene signature and validation of differential expression in hepatocellular carcinoma
por: Li, Yaoting, et al.
Publicado: (2023)

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unveils heterogeneity and establishes a novel signature for prognosis and tumor immune microenvironment in ovarian cancer
por: Wang, Zitao, et al.
Publicado: (2023)

RNA-SSNV: A Reliable Somatic Single Nucleotide Variant Identification Framework for Bulk RNA-Seq Data
por: Long, Qihan, et al.
Publicado: (2022)

Exploring PANoptosis in breast cancer based on scRNA-seq and bulk-seq
por: He, Puxing, et al.
Publicado: (2023)

Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer
por: Khong, Tak L, et al.
Publicado: (2013)

Characterization of cancer-related fibroblasts (CAF) in hepatocellular carcinoma and construction of CAF-based risk signature based on single-cell RNA-seq and bulk RNA-seq data
por: Yu, Lianghe, et al.
Publicado: (2022)

Evaluating the role of IDO1 macrophages in immunotherapy using scRNA-seq and bulk-seq in colorectal cancer
por: Liu, Xingwu, et al.
Publicado: (2022)

Integrated analysis of single-cell and bulk RNA-seq establishes a novel signature for prediction in gastric cancer
por: Wen, Fei, et al.
Publicado: (2023)

Mast cell marker gene signature: prognosis and immunotherapy response prediction in lung adenocarcinoma through integrated scRNA-seq and bulk RNA-seq
por: Zhang, Pengpeng, et al.
Publicado: (2023)

Integrated single-cell and bulk RNA sequencing analysis identifies a prognostic signature related to ferroptosis dependence in colorectal cancer
por: Xu, Xiaochen, et al.
Publicado: (2023)

Identification of a novel histone phosphorylation prognostic signature in hepatocellular carcinoma based on bulk and single-cell RNA sequencing
por: Fan, Lei, et al.
Publicado: (2022)

Integration of Bulk and Single-Cell RNA-Seq Data to Construct a Prognostic Model of Membrane Tension-Related Genes for Colon Cancer
por: Li, Jiacheng, et al.
Publicado: (2022)

Construction of cancer- associated fibroblasts related risk signature based on single-cell RNA-seq and bulk RNA-seq data in bladder urothelial carcinoma
por: Liu, Yunxun, et al.
Publicado: (2023)

SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data
por: Peng, Tao, et al.
Publicado: (2019)

A bioinformatics analysis of potential cellular communication networks in non-alcoholic steatohepatitis and colorectal adenoma using scRNA-seq and bulk-seq
por: Mo, Jiahao, et al.
Publicado: (2023)

Development and Validation of an RNA-Seq-Based Prognostic Signature in Neuroblastoma
por: Zhou, Jian-Guo, et al.
Publicado: (2019)

Integration of single-cell and bulk RNA-seq to establish a predictive signature based on the differentiation trajectory of M2 macrophages in lung adenocarcinoma
por: Chen, Zhike, et al.
Publicado: (2022)

A Novel Prognostic Model and Practical Nomogram for Predicting the Outcomes of Colorectal Cancer: Based on Tumor Biomarkers and Log Odds of Positive Lymph Node Scheme
por: Zhu, Jun, et al.
Publicado: (2021)

Development and validation of prognostic and diagnostic model for pancreatic ductal adenocarcinoma based on scRNA-seq and bulk-seq datasets
por: Chen, Kai, et al.
Publicado: (2021)

Delving into the Heterogeneity of Different Breast Cancer Subtypes and the Prognostic Models Utilizing scRNA-Seq and Bulk RNA-Seq
por: Xu, Jieyun, et al.
Publicado: (2022)

Hypoxia-Related Signature Is a Prognostic Biomarker of Pancreatic Cancer
por: Zhang, Jing-jing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pv3dgh7fi1eh7gnv8jqundj00u