The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion

Amorphous solid dispersion (ASD) is one of the most important strategies to improve the solubility and dissolution rate of poorly water-soluble drugs. As a widely used technique to prepare ASDs, hot-melt extrusion (HME) provides various benefits, including a solvent-free process, continuous manufact...

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Detalles Bibliográficos
Autores principales: Jiang, Junhuang, Lu, Anqi, Ma, Xiangyu, Ouyang, Defang, Williams, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925947/
https://www.ncbi.nlm.nih.gov/pubmed/36798832
http://dx.doi.org/10.1016/j.ijpx.2023.100164

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