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EDP‐297: A novel, farnesoid X receptor agonist—Results of a phase I study in healthy subjects

EDP‐297 is a farnesoid X receptor agonist under development for treating nonalcoholic steatohepatitis. The pharmacokinetic (PK), pharmacodynamic (PD), food effect, and safety were evaluated in a single ascending dose (SAD) and multiple ascending dose (MAD) phase I study. Healthy subjects received si...

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Detalles Bibliográficos
Autores principales:	Marotta, Christine, Ahmad, Alaa, Luo, Ed, Oosterhaven, Jart, van Marle, Sjoerd, Adda, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926082/ https://www.ncbi.nlm.nih.gov/pubmed/36369848 http://dx.doi.org/10.1111/cts.13453

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