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A Kmer-based paired-end read de novo assembler and genotyper for canine MHC class I genotyping

The major histocompatibility complex class I (MHC-I) genes are highly polymorphic. MHC-I genotyping is required for determining the peptide epitopes available to an individual’s T-cell repertoire. Current genotyping software tools do not work for the dog, due to very limited known canine alleles. To...

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Detalles Bibliográficos
Autores principales: Feng, Yuan, Hess, Paul R., Tompkins, Stephen M., Hildebrand, William H., Zhao, Shaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926114/
https://www.ncbi.nlm.nih.gov/pubmed/36798440
http://dx.doi.org/10.1016/j.isci.2023.105996