Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1

The kinetochore establishes the linkage between chromosomes and the spindle microtubule plus ends during mitosis. In vertebrates, the spindle-kinetochore–associated (Ska1,2,3) complex stabilizes kinetochore attachment with the microtubule plus ends, but how Ska is recruited to and stabilized at the...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Renjith M., Kizhakkeduth, Safwa T., Nair, Vishnu M., Ayyappan, Shine, Lakshmi, R. Bhagya, Babu, Neethu, Prasannajith, Anjaly, Umeda, Kenichi, Vijayan, Vinesh, Kodera, Noriyuki, Manna, Tapas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926122/
https://www.ncbi.nlm.nih.gov/pubmed/36592928
http://dx.doi.org/10.1016/j.jbc.2022.102853

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