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Esophageal ulcer associated with mild hemophilia A: case report

In this paper, we present the case of a 68-year-old male with personal medical history of coagulopathy issues, who presented to our Emergency Room (Emergency County Hospital, Arad, Romania) with bleeding of the superior tract of the digestive system; the case was difficult to manage, thus warranting...

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Autores principales: Nicolescu, Cristian Mircea, Neşiu, Alexandru, Uzum, Amelia, Laza, Damian Cristian, Nicolescu, Laura Corina, Freiman, Paul, Ardelean, Andrei, Ene, Răzvan, Marţi, Teodora Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926146/
https://www.ncbi.nlm.nih.gov/pubmed/36588498
http://dx.doi.org/10.47162/RJME.63.3.14
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author Nicolescu, Cristian Mircea
Neşiu, Alexandru
Uzum, Amelia
Laza, Damian Cristian
Nicolescu, Laura Corina
Freiman, Paul
Ardelean, Andrei
Ene, Răzvan
Marţi, Teodora Daniela
author_facet Nicolescu, Cristian Mircea
Neşiu, Alexandru
Uzum, Amelia
Laza, Damian Cristian
Nicolescu, Laura Corina
Freiman, Paul
Ardelean, Andrei
Ene, Răzvan
Marţi, Teodora Daniela
author_sort Nicolescu, Cristian Mircea
collection PubMed
description In this paper, we present the case of a 68-year-old male with personal medical history of coagulopathy issues, who presented to our Emergency Room (Emergency County Hospital, Arad, Romania) with bleeding of the superior tract of the digestive system; the case was difficult to manage, thus warranting the intervention of the Department of Gastroenterology. Endoscopy was performed to localize the site of bleeding and to stop the hemorrhage. This procedure was not successful. The patient was transferred to our Intensive Care Unit where different medications, such as proton pump inhibitor, hemostatic agent and prokinetic drugs were administered. Unfortunately, our attempt to stop bleeding failed; this led us to expand our investigation. We focused on a possible hemophilia as the cause of bleeding, which was confirmed as hemophilia A through the coagulometry test after a period of three days. Patient medical history and coagulation test led us to believe that this is a very rare case of a mild hemophilia A. Finally, the correction of Factor VIII deficiency and repeated endoscopic hemostasis clip was able to stop patients bleeding and ensured a favorable clinical evolution of the patient.
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spelling pubmed-99261462023-02-15 Esophageal ulcer associated with mild hemophilia A: case report Nicolescu, Cristian Mircea Neşiu, Alexandru Uzum, Amelia Laza, Damian Cristian Nicolescu, Laura Corina Freiman, Paul Ardelean, Andrei Ene, Răzvan Marţi, Teodora Daniela Rom J Morphol Embryol Case Report In this paper, we present the case of a 68-year-old male with personal medical history of coagulopathy issues, who presented to our Emergency Room (Emergency County Hospital, Arad, Romania) with bleeding of the superior tract of the digestive system; the case was difficult to manage, thus warranting the intervention of the Department of Gastroenterology. Endoscopy was performed to localize the site of bleeding and to stop the hemorrhage. This procedure was not successful. The patient was transferred to our Intensive Care Unit where different medications, such as proton pump inhibitor, hemostatic agent and prokinetic drugs were administered. Unfortunately, our attempt to stop bleeding failed; this led us to expand our investigation. We focused on a possible hemophilia as the cause of bleeding, which was confirmed as hemophilia A through the coagulometry test after a period of three days. Patient medical history and coagulation test led us to believe that this is a very rare case of a mild hemophilia A. Finally, the correction of Factor VIII deficiency and repeated endoscopic hemostasis clip was able to stop patients bleeding and ensured a favorable clinical evolution of the patient. Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2022 2022-09-30 /pmc/articles/PMC9926146/ /pubmed/36588498 http://dx.doi.org/10.47162/RJME.63.3.14 Text en Copyright © 2022, Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Case Report
Nicolescu, Cristian Mircea
Neşiu, Alexandru
Uzum, Amelia
Laza, Damian Cristian
Nicolescu, Laura Corina
Freiman, Paul
Ardelean, Andrei
Ene, Răzvan
Marţi, Teodora Daniela
Esophageal ulcer associated with mild hemophilia A: case report
title Esophageal ulcer associated with mild hemophilia A: case report
title_full Esophageal ulcer associated with mild hemophilia A: case report
title_fullStr Esophageal ulcer associated with mild hemophilia A: case report
title_full_unstemmed Esophageal ulcer associated with mild hemophilia A: case report
title_short Esophageal ulcer associated with mild hemophilia A: case report
title_sort esophageal ulcer associated with mild hemophilia a: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926146/
https://www.ncbi.nlm.nih.gov/pubmed/36588498
http://dx.doi.org/10.47162/RJME.63.3.14
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