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A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis

Engineered microbes for the delivery of biologics are a promising avenue for the treatment of various conditions such as chronic inflammatory disorders and metabolic disease. In this study, we developed a genetically engineered probiotic delivery system that delivers a peptide to the intestinal trac...

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Detalles Bibliográficos
Autores principales:	Wang, Yuqing, Zhu, Duolong, Ortiz-Velez, Laura C., Perry, Jacob L., Pennington, Michael W., Hyser, Joseph M., Britton, Robert A., Beeton, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926172/ https://www.ncbi.nlm.nih.gov/pubmed/36595694 http://dx.doi.org/10.1073/pnas.2211977120

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