Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis

Many epithelial compartments undergo constitutive renewal in homeostasis but activate unique regenerative responses following injury. The clear corneal epithelium is crucial for vision and is renewed from limbal stem cells (LSCs). Using single-cell RNA sequencing, we profiled the mouse corneal epith...

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Detalles Bibliográficos
Autores principales: Lin, Joseph B., Shen, Xiaolei, Pfeifer, Charles W., Shiau, Fion, Santeford, Andrea, Ruzycki, Philip A., Clark, Brian S., Liu, Qin, Huang, Andrew J. W., Apte, Rajendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926235/
https://www.ncbi.nlm.nih.gov/pubmed/36595669
http://dx.doi.org/10.1073/pnas.2204134120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926235/
https://www.ncbi.nlm.nih.gov/pubmed/36595669
http://dx.doi.org/10.1073/pnas.2204134120

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