Oligomer-to-monomer transition underlies the chaperone function of AAGAB in AP1/AP2 assembly

Assembly of protein complexes is facilitated by assembly chaperones. Alpha and gamma adaptin-binding protein (AAGAB) is a chaperone governing the assembly of the heterotetrameric adaptor complexes 1 and 2 (AP1 and AP2) involved in clathrin-mediated membrane trafficking. Here, we found that before AP...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Datta, Ishara, Yang, Rui, Wan, Chun, Wang, Bing, Crisman, Lauren, He, Huan, Brautigam, Chad A., Li, Suzhao, Shen, Jingshi, Yin, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926252/
https://www.ncbi.nlm.nih.gov/pubmed/36598941
http://dx.doi.org/10.1073/pnas.2205199120

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