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Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle
Hepatocellular carcinoma (HCC) remains a global health challenge whose incidence is growing worldwide. Previous evidence strongly supported the notion that the circadian clock controls physiological homeostasis of the liver and plays a key role in hepatocarcinogenesis. Despite the progress, cellular...
Autores principales: | Qu, Meng, Zhang, Guoxin, Qu, Han, Vu, Alexander, Wu, Raymond, Tsukamoto, Hidekazu, Jia, Zhenyu, Huang, Wendong, Lenz, Heinz-Josef, Rich, Jeremy N., Kay, Steve A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926257/ https://www.ncbi.nlm.nih.gov/pubmed/36595671 http://dx.doi.org/10.1073/pnas.2214829120 |
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