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Agonist of growth hormone-releasing hormone improves the disease features of spinal muscular atrophy mice
Spinal muscular atrophy (SMA) is a severe autosomal recessive neuromuscular disease affecting children and young adults, caused by mutations of the survival motor neuron 1 gene (SMN1). SMA is characterized by the degeneration of spinal alpha motor neurons (αMNs), associated with muscle paralysis and...
Autores principales: | Boido, Marina, Gesmundo, Iacopo, Caretto, Anna, Pedrolli, Francesca, Schellino, Roberta, Leone, Sheila, Cai, Renzhi, Sha, Wei, Ghigo, Ezio, Schally, Andrew V., Vercelli, Alessandro, Granata, Riccarda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926281/ https://www.ncbi.nlm.nih.gov/pubmed/36603028 http://dx.doi.org/10.1073/pnas.2216814120 |
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