Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL

Population studies have found that a natural human apoA-I variant, apoA-I[K107del], is strongly associated with low HDL-C but normal plasma apoA-I levels. We aimed to reveal properties of this variant that contribute to its unusual phenotype associated with atherosclerosis. Our oil-drop tensiometry...

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Detalles Bibliográficos
Autores principales: Gorshkova, Irina N., Meyers, Nathan L., Herscovitz, Haya, Mei, Xiaohu, Atkinson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926306/
https://www.ncbi.nlm.nih.gov/pubmed/36525992
http://dx.doi.org/10.1016/j.jlr.2022.100319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926306/
https://www.ncbi.nlm.nih.gov/pubmed/36525992
http://dx.doi.org/10.1016/j.jlr.2022.100319

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