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Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL

Population studies have found that a natural human apoA-I variant, apoA-I[K107del], is strongly associated with low HDL-C but normal plasma apoA-I levels. We aimed to reveal properties of this variant that contribute to its unusual phenotype associated with atherosclerosis. Our oil-drop tensiometry...

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Detalles Bibliográficos
Autores principales:	Gorshkova, Irina N., Meyers, Nathan L., Herscovitz, Haya, Mei, Xiaohu, Atkinson, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926306/ https://www.ncbi.nlm.nih.gov/pubmed/36525992 http://dx.doi.org/10.1016/j.jlr.2022.100319

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