Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages

Lysoplasmalogens are a class of vinyl ether bioactive lipids that have a central role in plasmalogen metabolism and membrane fluidity. The liver X receptor (LXR) transcription factors are important determinants of cellular lipid homeostasis owing to their ability to regulate cholesterol and fatty ac...

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Detalles Bibliográficos
Autores principales: van Wouw, Suzanne A.E., van den Berg, Marlene, El Ouraoui, Maroua, Meurs, Amber, Kingma, Jenina, Ottenhoff, Roelof, Loix, Melanie, Hoeksema, Marten A., Prange, Koen, Pasterkamp, Gerard, Hendriks, Jerome J.A., Bogie, Jeroen F.J., van Klinken, Jan B., Vaz, Frederic M., Jongejan, Aldo, de Winther, Menno P.J., Zelcer, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926310/
https://www.ncbi.nlm.nih.gov/pubmed/36592658
http://dx.doi.org/10.1016/j.jlr.2022.100325

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