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Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial

IMPORTANCE: Controlled clinical laboratory studies have shown that cannabidiol (CBD) can sometimes attenuate or exacerbate the effects of Δ9-tetrahydrocannabinol (Δ9-THC). No studies have evaluated differences in pharmacokinetics (PK) of Δ9-THC and pharmacodynamics (PD) between orally administered c...

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Detalles Bibliográficos
Autores principales:	Zamarripa, C. Austin, Spindle, Tory R., Surujunarain, Renuka, Weerts, Elise M., Bansal, Sumit, Unadkat, Jashvant D., Paine, Mary F., Vandrey, Ryan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926328/ https://www.ncbi.nlm.nih.gov/pubmed/36780161 http://dx.doi.org/10.1001/jamanetworkopen.2022.54752

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