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U1 snRNP proteins promote proximal alternative polyadenylation sites by directly interacting with 3′ end processing core factors

In eukaryotic cells, both alternative splicing and alternative polyadenylation (APA) play essential roles in the gene regulation network. U1 small ribonucleoprotein particle (U1 snRNP) is a major component of spliceosome, and U1 snRNP complex can suppress proximal APA sites through crosstalking with...

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Detalles Bibliográficos
Autores principales:	Hu, Zhijie, Li, Mengxia, Huo, Zhanfeng, Chen, Liutao, Liu, Susu, Deng, Ke, Lu, Xin, Chen, Shangwu, Fu, Yonggui, Xu, Anlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926334/ https://www.ncbi.nlm.nih.gov/pubmed/36073763 http://dx.doi.org/10.1093/jmcb/mjac054

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