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Modulation of Indoleamine 2,3-Dioxygenase 1 During Inflammatory Bowel Disease Activity in Humans and Mice

BACKGROUND AND AIMS: Indoleamine 2,3 dioxygenase-1 (IDO1), a key enzyme in tryptophan metabolism, is strongly up-regulated both in human inflammatory bowel disease (IBD) and animal models of colitis, however its role in the pathogenesis is still controversial. In this study, we investigated IDO1 exp...

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Detalles Bibliográficos
Autores principales:	Proietti, Elisa, Pauwels, Renske W.M., de Vries, Annemarie C., Orecchini, Elena, Volpi, Claudia, Orabona, Ciriana, Peppelenbosch, Maikel P., Fuhler, Gwenny M., Mondanelli, Giada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926376/ https://www.ncbi.nlm.nih.gov/pubmed/36798536 http://dx.doi.org/10.1177/11786469231153109

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