Asymmetric dysregulation of glutamate dynamics across the synaptic cleft in a mouse model of Alzheimer’s disease

Most research on glutamate spillover focuses on the deleterious consequences of postsynaptic glutamate receptor overactivation. However, two decades ago, it was noted that the glial coverage of hippocampal synapses is asymmetric: astrocytic coverage of postsynaptic sites exceeds coverage of presynap...

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Detalles Bibliográficos
Autores principales: Brymer, Kyle J., Hurley, Emily P., Barron, Jessica C., Mukherjee, Bandhan, Barnes, Jocelyn R., Nafar, Firoozeh, Parsons, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926626/
https://www.ncbi.nlm.nih.gov/pubmed/36788598
http://dx.doi.org/10.1186/s40478-023-01524-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926626/
https://www.ncbi.nlm.nih.gov/pubmed/36788598
http://dx.doi.org/10.1186/s40478-023-01524-x

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