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Atomic force microscopy reveals involvement of the cell envelope in biomechanical properties of sickle erythrocytes

BACKGROUND: Intracellular hemoglobin polymerization has been supposed to be the major determinant for the elevated rigidity/stiffness of sickle erythrocytes from sickle cell anemia (SCA) patients. However, the contribution of the cell envelope remains unclear. RESULTS: In this study, using atomic fo...

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Detalles Bibliográficos
Autores principales:	Wang, Kun, Li, Zhiqiang, Egini, Ogechukwu, Wadgaonkar, Raj, Jiang, Xian-Cheng, Chen, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926656/ https://www.ncbi.nlm.nih.gov/pubmed/36782158 http://dx.doi.org/10.1186/s12915-023-01523-3

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