Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models

Emergence of SARS-CoV-2 variants of concern (VOCs), including the highly transmissible Omicron and Delta strains, has posed constant challenges to the current COVID-19 vaccines that principally target the viral spike protein (S). Here, we report a nucleoside-modified messenger RNA (mRNA) vaccine tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Hajnik, Renee L., Plante, Jessica A., Liang, Yuejin, Alameh, Mohamad-Gabriel, Tang, Jinyi, Bonam, Srinivasa Reddy, Zhong, Chaojie, Adam, Awadalkareem, Scharton, Dionna, Rafael, Grace H., Liu, Yang, Hazell, Nicholas C., Sun, Jiaren, Soong, Lynn, Shi, Pei-Yong, Wang, Tian, Walker, David H., Sun, Jie, Weissman, Drew, Weaver, Scott C., Plante, Kenneth S., Hu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926941/
https://www.ncbi.nlm.nih.gov/pubmed/36103514
http://dx.doi.org/10.1126/scitranslmed.abq1945

Ejemplares similares

Ejemplares similares