Patient-derived monoclonal antibodies to SARS-CoV-2 nucleocapsid protein N-terminal and C-terminal domains cross-react with their counterparts of SARS-CoV, but not other human betacoronaviruses

INTRODUCTION: SARS-CoV-2 nucleocapsid (N) protein plays a key role in multiple stages of the viral life cycle such as viral replication and assembly. This protein is more conserved than the Spike protein of the virus and can induce both humoral and cell-mediated immune responses, thereby becoming a...

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Detalles Bibliográficos
Autores principales: Wen, Yingfen, Guo, Wenjing, Min, Yuyi, Zhong, Kexin, Zhang, Xulei, Xing, Xiaomin, Tong, Yuwei, Pan, Yuejun, Hong, Wenxin, Cai, Weiping, Yu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927002/
https://www.ncbi.nlm.nih.gov/pubmed/36798118
http://dx.doi.org/10.3389/fimmu.2023.1093709

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