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Rich Organic Nitrogen Impacts Clavulanic Acid Biosynthesis through the Arginine Metabolic Pathway in Streptomyces clavuligerus F613-1

Clavulanic acid (CA) is the preferred clinical drug for the treatment of infections by β-lactam antibiotic-resistant bacteria. CA is produced by Streptomyces clavuligerus, and although there have been many reports on the effects of carbon and nitrogen sources on CA production, the mechanisms involve...

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Detalles Bibliográficos
Autores principales:	Fu, Jiafang, Xie, Xinru, Zhang, Shaowei, Kang, Ni, Zong, Gongli, Zhang, Peipei, Cao, Guangxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927107/ https://www.ncbi.nlm.nih.gov/pubmed/36515504 http://dx.doi.org/10.1128/spectrum.02017-22

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