Umifenovir Epigenetically Targets the IL-10 Pathway in Therapy against Coxsackievirus B4 Infection

Umifenovir, a broad-spectrum nonnucleoside antiviral drug, has a promising efficacy against coxsackievirus B4 (CVB4) infection, but its mechanism remains unclear. CVB4 is a common human single-stranded RNA virus that belongs to the Picornaviridae family and the Enterovirus genus. Enterovirus can cau...

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Detalles Bibliográficos
Autores principales: Zhang, Shilin, Xue, Xiao, Qiao, Sennan, Jia, Lin, Wen, Xue, Wang, Yichen, Wang, Cong, Li, Hongrui, Cui, Jiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927110/
https://www.ncbi.nlm.nih.gov/pubmed/36541788
http://dx.doi.org/10.1128/spectrum.04248-22

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