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Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in OriLyt

Human cytomegalovirus (HCMV) is an opportunistic pathogen that infects most of the population. The complex 236 kbp genome encodes more than 170 open reading frames, whose expression is temporally regulated by both viral transcriptional regulators and cellular factors that control chromatin and trans...

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Detalles Bibliográficos
Autores principales: Forte, Eleonora, Li, Ming, Ayaloglu Butun, Fatma, Hu, Qiaolin, Borst, Eva Maria, Schipma, Matthew J., Piunti, Andrea, Shilatifard, Ali, Terhune, Scott S., Abecassis, Michael, Meier, Jeffery L., Hummel, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927211/
https://www.ncbi.nlm.nih.gov/pubmed/36645269
http://dx.doi.org/10.1128/spectrum.03144-22