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The exon-skipping oligonucleotide, KitStop, depletes tissue-resident mast cells in vivo to ameliorate anaphylaxis
INTRODUCTION: Anaphylaxis represents the most extreme and life-threatening form of allergic disease and is considered a medical emergency requiring immediate intervention. Additionally, some people with mastocytosis experience recurrent episodes of anaphylaxis during normal daily activities without...
Autores principales: | Hedgespeth, Barry A., Snider, Douglas B., Bitting, Katie J., Cruse, Glenn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927222/ https://www.ncbi.nlm.nih.gov/pubmed/36798116 http://dx.doi.org/10.3389/fimmu.2023.1006741 |
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