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In Vivo Gene Expression Profiling of Staphylococcus aureus during Infection Informs Design of Stemless Leukocidins LukE and -D as Detoxified Vaccine Candidates

Staphylococcus aureus is a clinically important bacterial pathogen that has become resistant to treatment with most routinely used antibiotics. Alternative strategies, such as vaccination and phage therapy, are therefore actively being investigated to prevent or combat staphylococcal infections. Vac...

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Detalles Bibliográficos
Autores principales: Haag, Andreas F., Liljeroos, Lassi, Donato, Paolo, Pozzi, Clarissa, Brignoli, Tarcisio, Bottomley, Matthew J., Bagnoli, Fabio, Delany, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927290/
https://www.ncbi.nlm.nih.gov/pubmed/36688711
http://dx.doi.org/10.1128/spectrum.02574-22