Cargando…

Clinical Diagnostic Performance of Droplet Digital PCR for Suspected Bloodstream Infections

Accurate and timely etiological diagnosis is crucial for bloodstream infections (BSIs) due to their high disability and mortality. We conducted a single-center prospective cohort study to compare the digital droplet PCR (ddPCR) assay with traditional blood culture. A total of 169 blood samples from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Ke, Zhao, Yuanhan, Xu, Bin, Yu, Shenglei, Fu, Zhangfan, Zhang, Yi, Wang, Hongyu, Song, Jieyu, Fan, Mingxiang, Zhou, Yang, Ai, Jingwen, Qiu, Chao, Zhang, Haocheng, Zhang, Wenhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927361/ https://www.ncbi.nlm.nih.gov/pubmed/36602351 http://dx.doi.org/10.1128/spectrum.01378-22

Ejemplares similares

Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern
por: Ai, Jingwen, et al.
Publicado: (2021)

Safety and immunogenicity of a third-dose homologous BBIBP-CorV boosting vaccination: interim results from a prospective open-label study
por: Ai, Jingwen, et al.
Publicado: (2022)

Utility of clinical metagenomics in diagnosing malignancies in a cohort of patients with Epstein-Barr virus positivity
por: Song, Jieyu, et al.
Publicado: (2023)

Clinical validation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections in ICU practice: a promising diagnostic tool
por: Wu, Jing, et al.
Publicado: (2022)

Clinical Application of a Multiplex Droplet Digital PCR in the Rapid Diagnosis of Children with Suspected Bloodstream Infections
por: Liu, Wenxin, et al.
Publicado: (2023)

Omicron variant showed lower neutralizing sensitivity than other SARS-CoV-2 variants to immune sera elicited by vaccines after boost
por: Ai, Jingwen, et al.
Publicado: (2022)

A diagnostic accuracy study comparing RNA LAMP, direct LAMP, and rapid antigen testing from nasopharyngeal swabs
por: Cao, Guojun, et al.
Publicado: (2022)

Evaluation of droplet digital PCR rapid detection method and precise diagnosis and treatment for suspected sepsis (PROGRESS): a study protocol for a multi-center pragmatic randomized controlled trial
por: Zhao, Yuanhan, et al.
Publicado: (2022)

Development and clinical validation of a droplet digital PCR assay for detecting Acinetobacter baumannii and Klebsiella pneumoniae in patients with suspected bloodstream infections
por: Zheng, Yang, et al.
Publicado: (2021)

Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling
por: Ai, Jingwen, et al.
Publicado: (2022)

Pathogen load and species monitored by droplet digital PCR in patients with bloodstream infections: A prospective case series study
por: Shao, Ziqiang, et al.
Publicado: (2022)

16S rDNA droplet digital PCR for monitoring bacterial DNAemia in bloodstream infections
por: Ziegler, Ingrid, et al.
Publicado: (2019)

A Comparison of Blood Pathogen Detection Among Droplet Digital PCR, Metagenomic Next-Generation Sequencing, and Blood Culture in Critically Ill Patients With Suspected Bloodstream Infections
por: Hu, Bangchuan, et al.
Publicado: (2021)

Natural History of and Dynamic Changes in Clinical Manifestation, Serology, and Treatment of Brucellosis, China
por: Wang, Hongyu, et al.
Publicado: (2022)

A comparison of ARMS-Plus and droplet digital PCR for detecting EGFR activating mutations in plasma
por: Zhang, Xinxin, et al.
Publicado: (2017)

Diagnostic utility of droplet digital PCR for HIV reservoir quantification
por: Trypsteen, Wim, et al.
Publicado: (2016)

SARS-CoV-2 intra-host single-nucleotide variants associated with disease severity
por: Zhang, Yi, et al.
Publicado: (2022)

Transgene Detection by Digital Droplet PCR
por: Moser, Dirk A., et al.
Publicado: (2014)

Quantification of HEV RNA by Droplet Digital PCR
por: Nicot, Florence, et al.
Publicado: (2016)

Detection of fish allergen by droplet digital PCR
por: Daga, Cinzia, et al.
Publicado: (2019)

Accurate bulk quantitation of droplet digital PCR
por: Sun, Chen, et al.
Publicado: (2021)

Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA
por: Zhang, Rui, et al.
Publicado: (2018)

Comparison of droplet digital PCR and conventional quantitative PCR for measuring EGFR gene mutation
por: ZHANG, BO, et al.
Publicado: (2015)

Droplet Digital PCR for BCR–ABL1 Monitoring in Diagnostic Routine: Ready to Start?
por: Bochicchio, Maria Teresa, et al.
Publicado: (2021)

Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas
por: Wolter, Marietta, et al.
Publicado: (2022)

Digital Droplet PCR for Detection and Quantitation of Hepatitis Delta Virus
por: Xu, Ling, et al.
Publicado: (2022)

Droplet digital PCR (ddPCR) for the detection and quantification of Ureaplasma spp.
por: Huang, Yanfang, et al.
Publicado: (2021)

Early identification and severity prediction of acute respiratory infection (ESAR): a study protocol for a randomized controlled trial
por: Yuan, Guanmin, et al.
Publicado: (2022)

Evaluation of Droplet Digital PCR Assay for the Diagnosis of Candidemia in Blood Samples
por: Chen, Biao, et al.
Publicado: (2021)

Diagnostic, Prognostic, and Therapeutic Value of Droplet Digital PCR (ddPCR) in COVID-19 Patients: A Systematic Review
por: Ishak, Angela, et al.
Publicado: (2021)

Diagnostic and prognostic microRNAs in the serum of breast cancer patients measured by droplet digital PCR
por: Mangolini, Alessandra, et al.
Publicado: (2015)

Droplet digital PCR for the detection and monitoring of Legionella pneumophila
por: Falzone, Luca, et al.
Publicado: (2020)

Meta-analysis of diagnostic performance of serology tests for COVID-19: impact of assay design and post-symptom-onset intervals
por: Wang, Hongyu, et al.
Publicado: (2020)

Droplet digital polymerase chain reaction for rapid broad‐spectrum detection of bloodstream infections
por: Wouters, Yannick, et al.
Publicado: (2019)

Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients
por: Alteri, Claudia, et al.
Publicado: (2020)

Absolute quantification by droplet digital PCR versus analog real-time PCR
por: Hindson, Christopher M, et al.
Publicado: (2013)

Maximizing viral detection with SIV droplet digital PCR (ddPCR) assays
por: Long, Samuel, et al.
Publicado: (2020)

Development of a droplet digital PCR method for detection of porcine circovirus 4
por: Liu, Yangkun, et al.
Publicado: (2023)

Identification and quantification of cassava starch adulteration in different food starches by droplet digital PCR
por: Chen, Jia, et al.
Publicado: (2020)

PoDCall: positive droplet calling and normalization of droplet digital PCR DNA methylation data
por: Jeanmougin, Marine, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t4cfs57n2gmtidgcu8cavotglr