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Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds

Collateral sensitivity (CS) is an evolutionary trade-off by which acquisition of resistance to an antibiotic leads to increased susceptibility to another. This Achilles’ heel of antibiotic resistance could be exploited to design evolution-based strategies for treating bacterial infections. To date,...

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Detalles Bibliográficos
Autores principales: Hernando-Amado, Sara, López-Causapé, Carla, Laborda, Pablo, Sanz-García, Fernando, Oliver, Antonio, Martínez, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927454/
https://www.ncbi.nlm.nih.gov/pubmed/36533961
http://dx.doi.org/10.1128/spectrum.02276-22

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