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Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds
Collateral sensitivity (CS) is an evolutionary trade-off by which acquisition of resistance to an antibiotic leads to increased susceptibility to another. This Achilles’ heel of antibiotic resistance could be exploited to design evolution-based strategies for treating bacterial infections. To date,...
Autores principales: | Hernando-Amado, Sara, López-Causapé, Carla, Laborda, Pablo, Sanz-García, Fernando, Oliver, Antonio, Martínez, José Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927454/ https://www.ncbi.nlm.nih.gov/pubmed/36533961 http://dx.doi.org/10.1128/spectrum.02276-22 |
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