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The Bacteriophage–Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases

Stl, the master repressor of the Staphylococcus aureus pathogenicity islands (SaPIs), targets phage-encoded proteins to derepress and synchronize the SaPI and the helper phage life cycles. To activate their cycle, some SaPI Stls target both phage dimeric and phage trimeric dUTPases (Duts) as antirep...

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Detalles Bibliográficos
Autores principales: Sanz-Frasquet, Carla, Ciges-Tomas, J. Rafael, Alite, Christian, Penadés, José R., Marina, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927489/
https://www.ncbi.nlm.nih.gov/pubmed/36622213
http://dx.doi.org/10.1128/spectrum.03232-22

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