Protease-Independent Production of Poliovirus Virus-like Particles in Pichia pastoris: Implications for Efficient Vaccine Development and Insights into Capsid Assembly

The production of enterovirus virus-like particles (VLPs) that lack the viral genome have great potential as vaccines for a number of diseases, such as poliomyelitis and hand, foot, and mouth disease. These VLPs can mimic empty capsids, which are antigenically indistinguishable from mature virions,...

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Detalles Bibliográficos
Autores principales: Sherry, Lee, Swanson, Jessica J., Grehan, Keith, Xu, Huijun, Uchida, Mai, Jones, Ian M., Stonehouse, Nicola J., Rowlands, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927490/
https://www.ncbi.nlm.nih.gov/pubmed/36507670
http://dx.doi.org/10.1128/spectrum.04300-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927490/
https://www.ncbi.nlm.nih.gov/pubmed/36507670
http://dx.doi.org/10.1128/spectrum.04300-22

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