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Three Amino Acid Substitutions in the Spike Protein Enable the Coronavirus Porcine Epidemic Diarrhea Virus To Infect Vero Cells

Porcine epidemic diarrhea virus (PEDV), a continuously evolving pathogen, causes severe diarrhea in piglets, with high mortality rates. To prevent or mitigate the disease, it is common practice to develop live or inactivated PEDV vaccines based on cell-adapted viral variants. Propagating wild-type P...

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Detalles Bibliográficos
Autores principales:	Chen, Bingqing, Dong, Shijuan, Yu, Li, Si, Fusheng, Li, Chunhua, Xie, Chunfang, Yu, Ruisong, Li, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927491/ https://www.ncbi.nlm.nih.gov/pubmed/36511700 http://dx.doi.org/10.1128/spectrum.03872-22

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