Goal-Directed Action Is Initially Impaired in a hAPP-J20 Mouse Model of Alzheimer’s Disease

Cognitive-behavioral testing in preclinical models of Alzheimer’s disease has failed to capture deficits in goal-directed action control. Here, we provide the first comprehensive investigation of goal-directed action in a transgenic mouse model of Alzheimer’s disease. Specifically, we tested outcome...

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Detalles Bibliográficos
Autores principales: Dhungana, Amolika, Becchi, Serena, Leake, Jessica, Morris, Gary, Avgan, Nesli, Balleine, Bernard W., Vissel, Bryce, Bradfield, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927544/
https://www.ncbi.nlm.nih.gov/pubmed/36650070
http://dx.doi.org/10.1523/ENEURO.0363-22.2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927544/
https://www.ncbi.nlm.nih.gov/pubmed/36650070
http://dx.doi.org/10.1523/ENEURO.0363-22.2023

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