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Goal-Directed Action Is Initially Impaired in a hAPP-J20 Mouse Model of Alzheimer’s Disease
Cognitive-behavioral testing in preclinical models of Alzheimer’s disease has failed to capture deficits in goal-directed action control. Here, we provide the first comprehensive investigation of goal-directed action in a transgenic mouse model of Alzheimer’s disease. Specifically, we tested outcome...
Autores principales: | Dhungana, Amolika, Becchi, Serena, Leake, Jessica, Morris, Gary, Avgan, Nesli, Balleine, Bernard W., Vissel, Bryce, Bradfield, Laura A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927544/ https://www.ncbi.nlm.nih.gov/pubmed/36650070 http://dx.doi.org/10.1523/ENEURO.0363-22.2023 |
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