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Discovery of Novel Transketolase Epitopes and the Development of IgG-Based Tuberculosis Serodiagnostics

Despite advances in rapid molecular techniques for tuberculosis (TB) diagnostics, there is an unmet need for a point-of-care, nonsputum-based test. Previously, through a T7 phage antigen display platform and immunoscreening, we identified that the serum IgGs of active TB patients differentially bind...

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Detalles Bibliográficos
Autores principales: Talreja, Jaya, Peng, Changya, Nguyen, Tuan-Minh, Draghici, Sorin, Samavati, Lobelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927582/
https://www.ncbi.nlm.nih.gov/pubmed/36651770
http://dx.doi.org/10.1128/spectrum.03377-22

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