Cargando…

N-Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus

The filamentous fungus Aspergillus flavus causes devastating diseases not only to cash crops but also to humans by secreting a series of secondary metabolites called aflatoxins. In the cotranslational or posttranslational process, N-myristoyltransferase (Nmt) is a crucial enzyme that catalyzes the m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yu, Lin, Ranxun, Liu, Mengxin, Wang, Sen, Chen, Hongyu, Zeng, Wanlin, Nie, Xinyi, Wang, Shihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927591/ https://www.ncbi.nlm.nih.gov/pubmed/36541770 http://dx.doi.org/10.1128/spectrum.04212-22

Ejemplares similares

The regulatory role of the Aspergillus flavus core retromer complex in aflatoxin metabolism
por: Wang, Sen, et al.
Publicado: (2022)

Glutamine Synthetase Contributes to the Regulation of Growth, Conidiation, Sclerotia Development, and Resistance to Oxidative Stress in the Fungus Aspergillus flavus
por: Wang, Sen, et al.
Publicado: (2022)

N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus
por: Fang, Wenxia, et al.
Publicado: (2015)

Lysine Succinylation Contributes to Aflatoxin Production and Pathogenicity in Aspergillus flavus
por: Ren, Silin, et al.
Publicado: (2018)

Essential APSES Transcription Factors for Mycotoxin Synthesis, Fungal Development, and Pathogenicity in Aspergillus flavus
por: Yao, Guangshan, et al.
Publicado: (2017)

aflN Is Involved in the Biosynthesis of Aflatoxin and Conidiation in Aspergillus flavus
por: Jia, Kunzhi, et al.
Publicado: (2021)

GTPase Rac Regulates Conidiation, AFB1 Production and Stress Response in Pathogenic Fungus Aspergillus flavus
por: Qin, Ling, et al.
Publicado: (2022)

Functional Analysis of the Nitrogen Metabolite Repression Regulator Gene nmrA in Aspergillus flavus
por: Han, Xiaoyun, et al.
Publicado: (2016)

Investigations on the Antifungal Effect of Nerol against Aspergillus flavus Causing Food Spoilage
por: Tian, Jun, et al.
Publicado: (2013)

In vitro antifungal susceptibility of clinical and environmental isolates of Aspergillus fumigatus and Aspergillus flavus in Brazil
por: Bedin Denardi, Laura, et al.
Publicado: (2017)

Functional Analysis of Peptidyl-prolyl cis-trans Isomerase from Aspergillus flavus
por: Ahmad, Saleem, et al.
Publicado: (2019)

The Mechanism of Antifungal Action of Essential Oil from Dill (Anethum graveolens L.) on Aspergillus flavus
por: Tian, Jun, et al.
Publicado: (2012)

Functional analyses of the versicolorin B synthase gene in Aspergillus flavus
por: Ren, Silin, et al.
Publicado: (2017)

RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection
por: Jiang, Yinhui, et al.
Publicado: (2023)

RNA-Seq-Based Transcriptome Analysis of Aflatoxigenic Aspergillus flavus in Response to Water Activity
por: Zhang, Feng, et al.
Publicado: (2014)

A Target Repurposing Approach Identifies N-myristoyltransferase as a New Candidate Drug Target in Filarial Nematodes
por: Galvin, Brendan D., et al.
Publicado: (2014)

Invasive Aspergillosis by Aspergillus flavus: Epidemiology, Diagnosis, Antifungal Resistance, and Management
por: Rudramurthy, Shivaprakash M., et al.
Publicado: (2019)

The DmtA methyltransferase contributes to Aspergillus flavus conidiation, sclerotial production, aflatoxin biosynthesis and virulence
por: Yang, Kunlong, et al.
Publicado: (2016)

The Stress Response Regulator AflSkn7 Influences Morphological Development, Stress Response, and Pathogenicity in the Fungus Aspergillus flavus
por: Zhang, Feng, et al.
Publicado: (2016)

Hydrophobic Effect of Amphiphilic Derivatives of Chitosan on the Antifungal Activity against Aspergillus flavus and Aspergillus parasiticus
por: Viegas de Souza, Ricchard Hallan Felix, et al.
Publicado: (2013)

Regulation of Morphology, Aflatoxin Production, and Virulence of Aspergillus flavus by the Major Nitrogen Regulatory Gene areA
por: Fasoyin, Opemipo Esther, et al.
Publicado: (2019)

The role of N-myristoyltransferase 1 in tumour development
por: Wang, Hong, et al.
Publicado: (2023)

Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani
por: Corpas-Lopez, Victoriano, et al.
Publicado: (2018)

Updates on the Functions and Molecular Mechanisms of the Genes Involved in Aspergillus flavus Development and Biosynthesis of Aflatoxins
por: Tumukunde, Elisabeth, et al.
Publicado: (2021)

The Aspergillus flavus Histone Acetyltransferase AflGcnE Regulates Morphogenesis, Aflatoxin Biosynthesis, and Pathogenicity
por: Lan, Huahui, et al.
Publicado: (2016)

Exploration of the Regulatory Mechanism of Secondary Metabolism by Comparative Transcriptomics in Aspergillus flavus
por: Yao, Guangshan, et al.
Publicado: (2018)

The Methyltransferase AflSet1 Is Involved in Fungal Morphogenesis, AFB1 Biosynthesis, and Virulence of Aspergillus flavus
por: Liu, Yaju, et al.
Publicado: (2020)

Inhibitor Trapping in N-Myristoyltransferases as a Mechanism for Drug Potency
por: Spassov, Danislav S., et al.
Publicado: (2023)

HexA is required for growth, aflatoxin biosynthesis and virulence in Aspergillus flavus
por: Yuan, Jun, et al.
Publicado: (2019)

Wheat pathogen Zymoseptoria tritici N-myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism
por: Fedoryshchak, Roman O., et al.
Publicado: (2020)

Integrated database for identifying candidate genes for Aspergillus flavus resistance in maize
por: Kelley, Rowena Y, et al.
Publicado: (2010)

UHPLC-HRMS-Based Untargeted Lipidomics Reveal Mechanism of Antifungal Activity of Carvacrol against Aspergillus flavus
por: Qu, Chenling, et al.
Publicado: (2021)

In Vitro Antifungal Activity of Peltophorum dubium (Spreng.) Taub. extracts against Aspergillus flavus
por: Di Ciaccio, Lucía S., et al.
Publicado: (2020)

Antifungal Activity of Essential Oil and Plant-Derived Natural Compounds against Aspergillus flavus
por: Tian, Fei, et al.
Publicado: (2022)

Antifungal Effect of Autochthonous Aromatic Plant Extracts on Two Mycotoxigenic Strains of Aspergillus flavus
por: Boy, Francisco Ramiro, et al.
Publicado: (2023)

Ssu72 Regulates Fungal Development, Aflatoxin Biosynthesis and Pathogenicity in Aspergillus flavus
por: Yang, Guang, et al.
Publicado: (2020)

AflSte20 Regulates Morphogenesis, Stress Response, and Aflatoxin Biosynthesis of Aspergillus flavus
por: Li, Ding, et al.
Publicado: (2019)

The Aspergillus flavus Phosphatase CDC14 Regulates Development, Aflatoxin Biosynthesis and Pathogenicity
por: Yang, Guang, et al.
Publicado: (2018)

The Putative Histone Methyltransferase DOT1 Regulates Aflatoxin and Pathogenicity Attributes in Aspergillus flavus
por: Liang, Linlin, et al.
Publicado: (2017)

Antifungal Activity of Essential Oil Compounds (Geraniol and Citral) and Inhibitory Mechanisms on Grain Pathogens (Aspergillus flavus and Aspergillus ochraceus)
por: Tang, Xi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cb3nuu30oprubl3p14r13t74sg