Cargando…
Analysis of IGH allele content in a sample group of rheumatoid arthritis patients demonstrates unrevealed population heterogeneity
Immunoglobulin heavy chain (IGH) germline gene variations influence the B cell receptor repertoire, with resulting biological consequences such as shaping our response to infections and altering disease susceptibilities. However, the lack of information on polymorphism frequencies in the IGH loci at...
Autores principales: | Hardt, Uta, Corcoran, Martin M., Narang, Sanjana, Malmström, Vivianne, Padyukov, Leonid, Karlsson Hedestam, Gunilla B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927645/ https://www.ncbi.nlm.nih.gov/pubmed/36798124 http://dx.doi.org/10.3389/fimmu.2023.1073414 |
Ejemplares similares
-
Adaptive immune receptor genotyping using the corecount program
por: Narang, Sanjana, et al.
Publicado: (2023) -
Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients
por: Houtman, Miranda, et al.
Publicado: (2021) -
High-Quality Library Preparation for NGS-Based Immunoglobulin Germline Gene Inference and Repertoire Expression Analysis
por: Vázquez Bernat, Néstor, et al.
Publicado: (2019) -
Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis
por: Hardt, Uta, et al.
Publicado: (2022) -
Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque
por: Kaduk, Mateusz, et al.
Publicado: (2022)