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Endothelial cell activation, Weibel-Palade body secretion, and enhanced angiogenesis in severe COVID-19
BACKGROUND: Severe COVID-19 is associated with marked endothelial cell (EC) activation that plays a key role in immunothrombosis and pulmonary microvascular occlusion. However, the biological mechanisms through which SARS-CoV-2 causes EC activation and damage remain poorly defined. OBJECTIVES: We in...
Autores principales: | Karampini, Ellie, Fogarty, Helen, Elliott, Stephanie, Morrin, Hannah, Bergin, Colm, O’Sullivan, Jamie M., Byrne, Mary, Martin-Loeches, Ignacio, Mallon, Patrick W., Curley, Gerard F., Glavey, Siobhan, Baker, Ross I., Lavin, M., Preston, Roger J.S., Cheallaigh, Cliona Ni, Ward, Soracha E., O’Donnell, James S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927806/ https://www.ncbi.nlm.nih.gov/pubmed/36817284 http://dx.doi.org/10.1016/j.rpth.2023.100085 |
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