UBC9 deficiency enhances immunostimulatory macrophage activation and subsequent antitumor T cell response in prostate cancer

The role of tumor-associated macrophages (TAMs), along with the regulatory mechanisms underlying distinct macrophage activation states, remains poorly understood in prostate cancer (PCa). Herein, we report that PCa growth in mice with macrophage-specific Ubc9 deficiency is substantially suppressed c...

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Detalles Bibliográficos
Autores principales: Xiao, Jun, Sun, Fei, Wang, Ya-Nan, Liu, Bo, Zhou, Peng, Wang, Fa-Xi, Zhou, Hai-Feng, Ge, Yue, Yue, Tian-Tian, Luo, Jia-Hui, Yang, Chun-Liang, Rong, Shan-Jie, Xiong, Ze-Zhong, Ma, Sheng, Zhang, Qi, Xun, Yang, Yang, Chun-Guang, Luan, Yang, Wang, Shao-Gang, Wang, Cong-Yi, Wang, Zhi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927932/
https://www.ncbi.nlm.nih.gov/pubmed/36626227
http://dx.doi.org/10.1172/JCI158352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927932/
https://www.ncbi.nlm.nih.gov/pubmed/36626227
http://dx.doi.org/10.1172/JCI158352

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