The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells

Ubiquitin-conjugating enzyme E2C (UBE2C) mediates ubiquitylation chain formation via the K11 linkage. While previous in vitro studies showed that UBE2C plays a growth-promoting role in cancer cell lines, the underlying mechanism remains elusive. Still unknown is whether and how UBE2C plays a promoti...

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Detalles Bibliográficos
Autores principales: Zhang, Shizhen, You, Xiahong, Zheng, Yawen, Shen, Yanwen, Xiong, Xiufang, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927933/
https://www.ncbi.nlm.nih.gov/pubmed/36548081
http://dx.doi.org/10.1172/JCI162434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927933/
https://www.ncbi.nlm.nih.gov/pubmed/36548081
http://dx.doi.org/10.1172/JCI162434

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