Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes

Diabetic nephropathy (DN) is a polygenic disorder with few risk variants showing robust replication in large-scale genome-wide association studies. To understand the role of DNA methylation, it is important to have the prevailing genomic view to distinguish key sequence elements that influence gene...

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Detalles Bibliográficos
Autores principales: Khurana, Ishant, Kaipananickal, Harikrishnan, Maxwell, Scott, Birkelund, Sørine, Syreeni, Anna, Forsblom, Carol, Okabe, Jun, Ziemann, Mark, Kaspi, Antony, Rafehi, Haloom, Jørgensen, Anne, Al-Hasani, Keith, Thomas, Merlin C., Jiang, Guozhi, Luk, Andrea O.Y., Lee, Heung Man, Huang, Yu, Thewjitcharoen, Yotsapon, Nakasatien, Soontaree, Himathongkam, Thep, Fogarty, Christopher, Njeim, Rachel, Eid, Assaad, Hansen, Tine Willum, Tofte, Nete, Ottesen, Evy C., Ma, Ronald C.W., Chan, Juliana C.N., Cooper, Mark E., Rossing, Peter, Groop, Per-Henrik, El-Osta, Assam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927943/
https://www.ncbi.nlm.nih.gov/pubmed/36633903
http://dx.doi.org/10.1172/JCI160959

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