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The mineralocorticoid receptor forms higher order oligomers upon DNA binding

The prevailing model of steroid hormone nuclear receptor function assumes ligand-induced homodimer formation followed by binding to DNA hormone response elements (HREs). This model has been challenged by evidence showing that the glucocorticoid receptor (GR) forms tetramers upon ligand and DNA bindi...

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Detalles Bibliográficos
Autores principales:	Fettweis, Gregory, Johnson, Thomas A., Almeida-Prieto, Brian, Presman, Diego M., Hager, Gordon L., Alvarez de la Rosa, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928021/ https://www.ncbi.nlm.nih.gov/pubmed/36789424 http://dx.doi.org/10.1101/2023.01.26.525752

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