Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells

Pro-inflammatory T cells co-express multiple chemokine receptors, but the distinct functions of individual receptors on these cells are largely unknown. Human Th17 cells uniformly express the chemokine receptor CCR6, and we discovered that the subgroup of CD4(+)CCR6(+) cells that co-express CCR2 pos...

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Detalles Bibliográficos
Autores principales: Parween, Farhat, Singh, Satya P., Zhang, Hongwei H, Kathuria, Nausheen, Otaizo-Carrasquero, Francisco A., Shamsaddini, Amirhossein, Gardina, Paul J., Ganesan, Sundar, Kabat, Juraj, Lorenzi, Hernan A., Myers, Timothy G., Farber, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928044/
https://www.ncbi.nlm.nih.gov/pubmed/36789428
http://dx.doi.org/10.1101/2023.01.25.525561

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