Effects of sex and APOE ε4 genotype on brain mitochondrial high-energy phosphates in midlife individuals at risk for Alzheimer’s disease: A (31)Phosphorus MR spectroscopy study

Age, female sex, and APOE epsilon 4 (APOE4) genotype are the three greatest risk factors for late-onset Alzheimer’s disease (AD). The convergence of these risks creates a hypometabolic AD-risk profile unique to women, which may help explain their higher lifetime risk of AD. Less is known about APOE4...

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Detalles Bibliográficos
Autores principales: Jett, Steven, Dyke, Jonathan P., Boneu Yepez, Camila, Zarate, Camila, Carlton, Caroline, Schelbaum, Eva, Jang, Grace, Pahlajani, Silky, Williams, Schantel, Diaz Brinton, Roberta, Mosconi, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928085/
https://www.ncbi.nlm.nih.gov/pubmed/36787293
http://dx.doi.org/10.1371/journal.pone.0281302

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